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链格孢菌皮肤感染并发免疫抑制:伊曲康唑治疗成功

Cutaneous infection with Alternaria alternata complicating immunosuppression: successful treatment with itraconazole.

作者信息

Acland K M, Hay R J, Groves R

机构信息

Department of Dermatology, UCL Hospitals Trust, London, U.K.

出版信息

Br J Dermatol. 1998 Feb;138(2):354-6. doi: 10.1046/j.1365-2133.1998.02091.x.

DOI:10.1046/j.1365-2133.1998.02091.x
PMID:9602891
Abstract

We report an immunosuppressed patient who presented with unusual leg ulceration caused by Alternaria alternata infection. Alternaria is a common saprophyte that is not usually pathogenic in humans. However, infections have previously been documented. Most cases occur in immunocompromised patients and the skin manifestations may vary considerably. The diagnosis is often missed initially as it is not frequently suspected. The treatment is controversial both in choice of agent used and in duration of therapy.

摘要

我们报告了一名免疫抑制患者,其因链格孢菌感染出现了罕见的腿部溃疡。链格孢菌是一种常见的腐生菌,通常对人类无致病性。然而,此前已有感染的记录。大多数病例发生在免疫功能低下的患者中,皮肤表现可能有很大差异。由于最初常常未被怀疑,诊断往往一开始就被漏诊。在治疗药物的选择和治疗持续时间方面,治疗都存在争议。

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