Lo Cascio G, Ligozzi M, Maccacaro L, Fontana R
Servizio di Microbiologia, Azienda Ospedaliera di Verona, Ospedale Policlinico G. B. Rossi, Piazzale Scuro, 10, 37134 Verona, Italy.
J Clin Microbiol. 2004 Nov;42(11):5334-6. doi: 10.1128/JCM.42.11.5334-5336.2004.
We report on a case of cutaneous infection caused by Alternaria infectoria in a cardiac transplant recipient. A rapid molecular diagnosis was obtained by sequence analysis of the internal transcribed spacer domain of the 5.8S ribosomal DNA region amplified from colonies developed on Sabouraud medium. Treatment consisted of a combination of systemic antifungal therapy, first with amphotericin B and then with itraconazole.
我们报告了一例心脏移植受者感染链格孢菌引起皮肤感染的病例。通过对在沙氏培养基上生长的菌落中扩增出的5.8S核糖体DNA区域的内转录间隔区进行序列分析,快速做出了分子诊断。治疗采用全身性抗真菌治疗联合用药,先是两性霉素B,然后是伊曲康唑。