恶性疟原虫：IgM在寄生虫感染红细胞玫瑰花结形成中的重要性。 - Suppr

Plasmodium falciparum: the importance of IgM in the rosetting of parasite-infected erythrocytes.

作者信息

Clough B, Atilola F A, Black J, Pasvol G

机构信息

Department of Infection and Tropical Medicine, Imperial College School of Medicine, Northwick Park and St. Mark's Hospital, Harrow, Middlesex, United Kingdom.

出版信息

Exp Parasitol. 1998 May;89(1):129-32. doi: 10.1006/expr.1998.4275.

DOI:10.1006/expr.1998.4275

PMID:9603499

Abstract

摘要

相似文献

Plasmodium falciparum: the importance of IgM in the rosetting of parasite-infected erythrocytes.恶性疟原虫：IgM在寄生虫感染红细胞玫瑰花结形成中的重要性。

Exp Parasitol. 1998 May;89(1):129-32. doi: 10.1006/expr.1998.4275.

Nonimmune IgM, but not IgG binds to the surface of Plasmodium falciparum-infected erythrocytes and correlates with rosetting and severe malaria.非免疫性IgM而非IgG可结合到恶性疟原虫感染的红细胞表面，并与红细胞凝聚及重症疟疾相关。

Am J Trop Med Hyg. 2002 Jun;66(6):692-9. doi: 10.4269/ajtmh.2002.66.692.

Plasmodium falciparum: immune pressure in Saimiri sciureus monkeys can select for a parasite population inducing a protective immunity that is not controlled by antibody.恶性疟原虫：松鼠猴体内的免疫压力可选择出一种寄生虫群体，该群体可诱导产生不受抗体控制的保护性免疫。

Exp Parasitol. 1998 Sep;90(1):49-57. doi: 10.1006/expr.1998.4318.

Complement factor D, albumin, and immunoglobulin G anti-band 3 protein antibodies mimic serum in promoting rosetting of malaria-infected red blood cells.补体因子D、白蛋白和免疫球蛋白G抗带3蛋白抗体在促进疟疾感染红细胞的玫瑰花结形成方面模拟血清。

Infect Immun. 2007 Apr;75(4):1771-7. doi: 10.1128/IAI.01514-06. Epub 2007 Jan 29.

Rouleaux-forming serum proteins are involved in the rosetting of Plasmodium falciparum-infected erythrocytes.形成缗钱状的血清蛋白参与恶性疟原虫感染红细胞的玫瑰花结形成。

Exp Parasitol. 1999 Dec;93(4):215-24. doi: 10.1006/expr.1999.4454.

Rosetting in Plasmodium falciparum: a cytoadherence phenotype with multiple actors.恶性疟原虫中的红细胞凝集：一种由多种因素导致的细胞黏附表型

Transfus Clin Biol. 2008 Feb-Mar;15(1-2):62-71. doi: 10.1016/j.tracli.2008.04.003. Epub 2008 Jun 2.

Rosetting of Plasmodium falciparum required multiple components of the uninfected erythrocytes.恶性疟原虫的红细胞凝集需要未感染红细胞的多种成分。

Asian Pac J Allergy Immunol. 2000 Mar;18(1):29-35.

Immunization with PfEMP1-DBL1alpha generates antibodies that disrupt rosettes and protect against the sequestration of Plasmodium falciparum-infected erythrocytes.用PfEMP1-DBL1α进行免疫接种可产生抗体，这些抗体可破坏玫瑰花结形成，并防止恶性疟原虫感染的红细胞发生滞留。

Vaccine. 2004 Jul 29;22(21-22):2701-12. doi: 10.1016/j.vaccine.2004.02.015.

Nonimmune immunoglobulin binding and multiple adhesion characterize Plasmodium falciparum-infected erythrocytes of placental origin.非免疫性免疫球蛋白结合和多种黏附特性是胎盘来源的恶性疟原虫感染红细胞的特征。

Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13795-800. doi: 10.1073/pnas.0601519103. Epub 2006 Aug 31.

Antibodies from malaria-exposed pregnant women recognize trypsin resistant epitopes on the surface of Plasmodium falciparum-infected erythrocytes selected for adhesion to chondroitin sulphate A.来自接触过疟疾的孕妇的抗体能够识别恶性疟原虫感染的红细胞表面上对胰蛋白酶具有抗性的表位，这些红细胞是被选择用于黏附硫酸软骨素A的。

Malar J. 2004 Sep 6;3:31. doi: 10.1186/1475-2875-3-31.

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The role of periostin (OSF-2) in the cytoadherence phenomena mediated by malaria parasites.骨膜蛋白（骨涎蛋白-2）在疟原虫介导的细胞黏附现象中的作用。

Front Cell Infect Microbiol. 2025 May 13;15:1599872. doi: 10.3389/fcimb.2025.1599872. eCollection 2025.

Erythrocyte miRNA-92a-3p interactions with PfEMP1 as determinants of clinical malaria.红细胞 miRNA-92a-3p 与 PfEMP1 的相互作用是临床疟疾的决定因素。

Funct Integr Genomics. 2023 Mar 20;23(2):93. doi: 10.1007/s10142-023-01028-w.

VAR2CSA-Mediated Host Defense Evasion of Infected Erythrocytes in Placental Malaria.VAR2CSA 介导的胎盘疟疾感染红细胞的宿主防御逃避。

Front Immunol. 2021 Feb 9;11:624126. doi: 10.3389/fimmu.2020.624126. eCollection 2020.

Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it.恶性疟原虫性脑型疟疾：PfEMP1 在其发病机制和免疫中的作用，以及基于 PfEMP1 的疫苗来预防它。

Immunol Rev. 2020 Jan;293(1):230-252. doi: 10.1111/imr.12807. Epub 2019 Sep 27.

Reduced Expression of Is Associated with the Phenotype of a Flower-Defective .下调的表达与花缺陷表型相关。

Int J Mol Sci. 2019 May 21;20(10):2503. doi: 10.3390/ijms20102503.

Examining the Reticulocyte Preference of Two Strains during Blood-Stage Malaria Infection.研究两种菌株在血液期疟疾感染过程中的网织红细胞偏好性。

Front Microbiol. 2018 Feb 20;9:166. doi: 10.3389/fmicb.2018.00166. eCollection 2018.

Variant surface antigens of Plasmodium falciparum and their roles in severe malaria.恶性疟原虫表面抗原变异及其在重症疟疾中的作用。

Nat Rev Microbiol. 2017 Aug;15(8):479-491. doi: 10.1038/nrmicro.2017.47. Epub 2017 Jun 12.

Functional analysis of monoclonal antibodies against the Plasmodium falciparum PfEMP1-VarO adhesin.针对恶性疟原虫PfEMP1-VarO黏附素的单克隆抗体的功能分析

Malar J. 2016 Jan 15;15:28. doi: 10.1186/s12936-015-1016-5.

Evasion of Immunity to Plasmodium falciparum: Rosettes of Blood Group A Impair Recognition of PfEMP1.恶性疟原虫免疫逃逸：A 血型红细胞玫瑰花结损害对 PfEMP1 的识别。

PLoS One. 2015 Dec 29;10(12):e0145120. doi: 10.1371/journal.pone.0145120. eCollection 2015.

Genetic Resistance to Malaria Is Associated With Greater Enhancement of Immunoglobulin (Ig)M Than IgG Responses to a Broad Array of Plasmodium falciparum Antigens.遗传抗性对疟疾的影响与增强针对广泛的疟原虫抗原的免疫球蛋白 (Ig)M 反应有关，甚于 IgG 反应。

Open Forum Infect Dis. 2015 Aug 26;2(3):ofv118. doi: 10.1093/ofid/ofv118. eCollection 2015 Sep.

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Plasmodium falciparum: the importance of IgM in the rosetting of parasite-infected erythrocytes.

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