Subungual squamous cell carcinoma in Darier's disease.
作者信息
Downs A M, Ward K A, Peachey R D
机构信息
Department of Dermatology, Bristol Royal Infirmary, UK.
出版信息
Clin Exp Dermatol. 1997 Nov;22(6):277-9.
PMID:9604454
Abstract
We report the first case of subungual squamous cell carcinoma in a patient with Darier's disease (keratosis follicularis). The presence of human papillomavirus DNA was confirmed, consistent with its probable role in carcinogenesis at this site. The role of an altered immune state is discussed as an additional factor. Squamous cell carcinomas may be overlooked when they occur among the other cutaneous manifestations and complications of Darier's disease. A solitary, ulcerating nail bed lesion warrants biopsy to exclude squamous cell carcinoma.
摘要
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