Leksa V, Altaner C
Cancer Research Institute, Slovak Academy of Sciences, Bratislava.
Neoplasma. 1997;44(6):337-41.
Differential display technique was applied to study expression of RNA in tumorigenic and nontumorigenic cell variants of avian sarcoma virus transformed hamster cells. Methodical conditions were worked out, which allowed identifying a cDNA fragment of an unknown gene expressed in nontumorigenic cell variant only. Its role in tumor suppression remains to be determined.
应用差异显示技术研究禽肉瘤病毒转化的仓鼠细胞的致瘤性和非致瘤性细胞变体中RNA的表达。制定了方法条件，从而能够鉴定出仅在非致瘤性细胞变体中表达的一个未知基因的cDNA片段。其在肿瘤抑制中的作用尚待确定。
