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针对非裔美国青少年的禁欲和安全性行为降低艾滋病病毒风险干预措施:一项随机对照试验。

Abstinence and safer sex HIV risk-reduction interventions for African American adolescents: a randomized controlled trial.

作者信息

Jemmott J B, Jemmott L S, Fong G T

机构信息

Department of Psychology, Princeton University, NJ 08544-1010, USA.

出版信息

JAMA. 1998 May 20;279(19):1529-36. doi: 10.1001/jama.279.19.1529.

Abstract

CONTEXT

African American adolescents are at high risk of contracting sexually transmitted infection with human immunodeficiency virus (HIV), but which behavioral interventions to reduce risk are most effective and who should conduct them is not known.

OBJECTIVE

To evaluate the effects of abstinence and safer-sex HIV risk-reduction interventions on young inner-city African American adolescents' HIV sexual risk behaviors when implemented by adult facilitators as compared with peer cofacilitators.

DESIGN

Randomized controlled trial with 3-, 6-, and 12-month follow-up.

SETTING

Three middle schools serving low-income African American communities in Philadelphia, Pa.

PARTICIPANTS

A total of 659 African American adolescents recruited for a Saturday program.

INTERVENTIONS

Based on cognitive-behavioral theories and elicitation research, interventions involved 8 1-hour modules implemented by adult facilitators or peer cofacilitators. Abstinence intervention stressed delaying sexual intercourse or reducing its frequency; safer-sex intervention stressed condom use; control intervention concerned health issues unrelated to sexual behavior.

MAIN OUTCOME MEASURES

Self-reported sexual intercourse, condom use, and unprotected sexual intercourse.

RESULTS

Mean age of the enrollees was 11.8 years; 53% were female and 92.6% were still enrolled at 12 months. Abstinence intervention participants were less likely to report having sexual intercourse in the 3 months after intervention than were control group participants (12.5% vs 21.5%, P=.02), but not at 6- or 12-month follow-up (17.2% vs 22.7%, P=.14; 20.0% vs 23.1%, P=.42, respectively). Safer-sex intervention participants reported significantly more consistent condom use than did control group participants at 3 months (odds ratio [OR]=3.38; 95% confidence interval [CI], 1.25-9.16) and higher frequency of condom use at all follow-ups. Among adolescents who reported sexual experience at baseline, the safer-sex intervention group reported less sexual intercourse in the previous 3 months at 6- and 12-month follow-up than did control and abstinence intervention (adjusted mean days over prior 3 months, 1.34 vs 3.77 and 3.03, respectively; P< or =.01 at 12- month follow-up) and less unprotected intercourse at all follow-ups than did control group (adjusted mean days, 0.04 vs 1.85, respectively, P<.001, at 12-month follow-up). There were no differences in intervention effects with adult facilitators as compared with peer cofacilitators.

CONCLUSION

Both abstinence and safer-sex interventions can reduce HIV sexual risk behaviors, but safer-sex interventions may be especially effective with sexually experienced adolescents and may have longer-lasting effects.

摘要

背景

非裔美国青少年感染人类免疫缺陷病毒(HIV)性传播感染的风险很高,但尚不清楚哪些降低风险的行为干预措施最有效以及应由谁来实施这些措施。

目的

评估由成人辅导员与同伴共同辅导员实施的禁欲和安全性行为降低HIV风险干预措施对市中心贫困非裔美国青少年HIV性风险行为的影响。

设计

随机对照试验,随访3个月、6个月和12个月。

地点

宾夕法尼亚州费城为低收入非裔美国社区服务的三所中学。

参与者

共有659名非裔美国青少年参加了一个周六项目。

干预措施

基于认知行为理论和诱导研究,干预措施包括由成人辅导员或同伴共同辅导员实施的8个1小时的模块。禁欲干预强调推迟性行为或减少性行为频率;安全性行为干预强调使用避孕套;对照干预关注与性行为无关的健康问题。

主要观察指标

自我报告的性行为、避孕套使用情况和无保护性行为。

结果

参与者的平均年龄为11.8岁;53%为女性,92.6%在12个月时仍在参与项目。禁欲干预参与者在干预后3个月内报告有性行为的可能性低于对照组参与者(12.5%对21.5%,P = 0.02),但在6个月或12个月随访时并非如此(分别为17.2%对22.7%,P = 0.14;20.0%对23.1%,P = 0.42)。安全性行为干预参与者在3个月时报告的避孕套使用一致性显著高于对照组参与者(优势比[OR]=3.38;95%置信区间[CI],1.25 - 9.16),并且在所有随访中避孕套使用频率更高。在基线报告有性经历的青少年中,安全性行为干预组在6个月和12个月随访时报告的前3个月内性行为少于对照组和禁欲干预组(调整后的前3个月平均天数分别为1.34天对3.77天和3.03天;12个月随访时P≤0.01),并且在所有随访中无保护性行为少于对照组(12个月随访时调整后的平均天数分别为0.04天对1.85天,P<0.001)。与同伴共同辅导员相比,成人辅导员的干预效果没有差异。

结论

禁欲和安全性行为干预都可以降低HIV性风险行为,但安全性行为干预对有性经历的青少年可能特别有效,并且可能具有更持久的效果。

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