细胞因子对人小胶质细胞抗隐球菌活性的影响。
Effect of cytokines on anticryptococcal activity of human microglial cells.
作者信息
Lipovsky M M, Juliana A E, Gekker G, Hu S, Hoepelman A I, Peterson P K
机构信息
Neuroimmunobiology and Host Defense Laboratory, Minneapolis Medical Research Foundation, Minnesota, USA.
出版信息
Clin Diagn Lab Immunol. 1998 May;5(3):410-1. doi: 10.1128/CDLI.5.3.410-411.1998.
Abstract
The effect of selected cytokines on the antifungal activity of human microglia was studied with encapsulated and acapsular strains of Cryptococcus neoformans. None of the cytokines tested increased the fungistatic activity of microglia, suggesting that killing of cryptococci within the central nervous system is dependent on other host defense mechanisms.
摘要
选用新型隐球菌的包膜菌株和无包膜菌株，研究了特定细胞因子对人小胶质细胞抗真菌活性的影响。所测试的细胞因子均未增强小胶质细胞的抑菌活性，这表明中枢神经系统内隐球菌的杀灭依赖于其他宿主防御机制。
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