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[维生素D代谢产物对慢性肾功能衰竭患儿蛋白质、钙和磷周转标志物的影响]

[Effect of vitamin D metabolites on the markers of protein, calcium and phosphorus turnover in children with chronic renal failure].

作者信息

Denisova S N, Kutafina E K, Sergeeva T V, Savina M I, Kon' I Ia, Shilina N M, Chizhevskaia O L, Shilov A V

出版信息

Vopr Pitan. 1998(1):14-7.

PMID:9606860
Abstract

Amino acid analysis and investigation of nitrogen, calcium and phosphorus balance were done in two groups of the patients with renal failure and osteodystrophy on the Vitamin D metabolites and analogues treatment. The results of the investigation confirm vitamin D metabolites influence on free amino acid turnover and on nitrogen, calcium, phosphorus balance. We observed significant decreases of blood amino acids and good influence on renal osteodystrophy in patients treated with the vitamin D metabolites. Vitamin D metabolites didn't influence on the retention, urinary and fecal excretion of endogenous nitrogen in patients with renal failure.

摘要

对两组接受维生素D代谢物和类似物治疗的肾衰竭和骨营养不良患者进行了氨基酸分析以及氮、钙和磷平衡的研究。研究结果证实了维生素D代谢物对游离氨基酸周转以及氮、钙、磷平衡的影响。我们观察到接受维生素D代谢物治疗的患者血液氨基酸显著减少,且对肾性骨营养不良有良好影响。维生素D代谢物对肾衰竭患者内源性氮的潴留、尿排泄和粪排泄没有影响。

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