Alimbarova L M, Barinskiĭ I F, Kuz'min K K
Vopr Virusol. 1998 Mar-Apr;43(2):82-6.
Antiviral activity of a Russian drug foscarnet (tablets and coated pills) was assessed in guinea pigs with experimental genital herpes. New dosage forms were well tolerated by the animals, causing no manifest symptoms of intoxication irrespective of the doses or protocols of the drug use, Foscarnet in any dosage form in the total daily dose of at least 120 mg/kg had a pronounced antiviral effect towards herpes simplex type II virus, comparable with that of the commercial reference drug virolex: the intensity of clinical symptoms was alleviated and the disease duration shortened.
在患有实验性生殖器疱疹的豚鼠身上评估了俄罗斯药物膦甲酸钠（片剂和包衣丸剂）的抗病毒活性。新剂型的药物在动物身上耐受性良好，无论使用的剂量或方案如何，均未引起明显的中毒症状。任何剂型的膦甲酸钠，每日总剂量至少为120mg/kg时，对II型单纯疱疹病毒都有显著的抗病毒作用，与市售参比药物维洛昔韦相当：临床症状的严重程度减轻，疾病持续时间缩短。
