Marennikova S S, Matsevich G R, Chekunova E V, Nikulina V G, Rozina E E
Vopr Virusol. 1986 Jan-Feb;31(1):59-65.
New experimental models of neurological herpes in cotton rats and genital herpes in male guinea pigs have been developed which are more adequate to the corresponding human diseases, and models of ophthalmic herpes in rabbits and guinea pigs have been improved. These models may be used for screening and evaluation of the effectiveness of drugs for herpes. A high activity against herpes of bromovinyldeoxyuridine and acyclovir has been verified, a marked therapeutic effect of Soviet monophosphates ara-A, ara-C, and original silur preparation in some forms of herpes infection has been demonstrated.
已经开发出了更适合相应人类疾病的棉鼠神经性疱疹和雄性豚鼠生殖器疱疹的新实验模型，并且改进了兔和豚鼠眼部疱疹的模型。这些模型可用于筛选和评估抗疱疹药物的有效性。已证实溴乙烯脱氧尿苷和阿昔洛韦对疱疹具有高活性，已证明苏联的阿糖腺苷单磷酸盐、阿糖胞苷和原始的鲇鱼制剂在某些形式的疱疹感染中具有显著的治疗效果。
