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[血色素沉着症中内脏器官的形态学变化]

[The morphological changes in the internal organs in hemochromatosis].

作者信息

Pigolkin Iu I, Osipenkova T K

出版信息

Sud Med Ekspert. 1998 Mar-Apr;41(2):20-2.

PMID:9608256
Abstract

Visceral changes were studied by histological and electron-microscopic methods in cadavers of 18 subjects dead from hemochromatosis. Pronounced visceral changes in all cases represented a characteristic tetrad of signs: bronze-colored skin, pigmentary cirrhosis of the liver, involvement of the pancreas, and cardiomyopathy. In forensic medical practice hemochromatosis can be found in subjects who were probably genetically predisposed to it and, as a rule, had a history of alcohol abuse. Among the numerous complications of the disease, the most incident are cardiac pathology (dilatation cardiomyopathy) and diabetes mellitus with concomitant intoxications caused by various inflammations.

摘要

通过组织学和电子显微镜方法,对18例死于血色素沉着症患者的尸体进行了内脏变化研究。所有病例中明显的内脏变化呈现出特征性的四联征:皮肤青铜色、肝色素性肝硬化、胰腺受累和心肌病。在法医学实践中,血色素沉着症可见于可能具有遗传易感性且通常有酗酒史的个体。在该疾病的众多并发症中,最常见的是心脏病变(扩张型心肌病)和糖尿病以及由各种炎症引起的中毒。

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