Does the latency associated transcript (LAT) of herpes simplex virus (HSV) function as a ribozyme during viral reactivation?
作者信息
Hui E K, Lo S J
机构信息
Institute of Microbiology and Immunology (IMI), School of Life Science, National Yang-Ming University (NYMU), Taipei, Taiwan, Republic of China.
出版信息
Virus Genes. 1998;16(2):147-8. doi: 10.1023/a:1007937521771.
PMID:9608658
Abstract
The latency associated transcript (LAT) of herpes simplex virus (HSV) appears to exist as an RNA molecule only. This phenomenon is consistent with the concept of functioning at an RNA level, and several lines of evidence suggest that the LAT may be a ribozyme. This provides an insight into understanding the role of LAT during HSV reactivation.
摘要
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