Thiele G, Fiedler H
Z Gesamte Inn Med. 1976 Jul 15;31(14):542-4.
The demonstration of monomeric complexes of fibrin in the blood is regarded as a secure sign of an increased consumption of coagulation factors in the sense of a consumption coagulopathy. As a simple and sensitive method for the demonstration of these intermediate products of the coagulation the protamine sulphate test proved its worth in clinical practice. The subjective judgment of this test-tube test frequently becomes difficult in the borderline region between normal and pathologic. On the basis of own comparative investigations it could, however, be demonstrated that by means of photometric measurements an objective and exact evidence about the result of the protamine sulphate test can be made. It is referred to the advantages in the judgment of the course of a consumption coagulopathy during the treatment.
血液中纤维蛋白单体复合物的出现被视为在消耗性凝血病意义上凝血因子消耗增加的确切迹象。作为一种检测这些凝血中间产物的简单而灵敏的方法，硫酸鱼精蛋白试验在临床实践中证明了其价值。这种试管试验的主观判断在正常与病理的临界区域常常变得困难。然而，根据自身的比较研究可以证明，通过光度测量能够对硫酸鱼精蛋白试验的结果做出客观准确的判定。文中提到了在治疗过程中判断消耗性凝血病病程方面的优势。
