Böhmer R, Binder R, Rommel K, Dietrich M, Wolf G
Z Gastroenterol. 1976 Jan;14(1):30-40.
The influence of the bacterial flora of the intestine and of cytostatic drugs on the intestinal xylose and glucose absorption in the rat is studied by a perfusion technique in vivo. Conventional, germfree and decontaminated animals show no different xylose absorption rates while the galactose absorption is decreased in germfree and decontaminated animals compared to conventional rats. Three days after a single injection of cytostatic drugs the xylose absorption is diminished in conventional and decontaminated animals compared to untreated rats. In germfree rats no effect of cytostatics on the xylose absorption can be proved. The galactose absorption is unchanged after cytostatics in conventional and decontaminated animals, but increased in germfree rats.
采用体内灌注技术研究了肠道菌群和细胞抑制药物对大鼠肠道木糖和葡萄糖吸收的影响。普通、无菌和净化动物的木糖吸收速率无差异，而无菌和净化动物的半乳糖吸收与普通大鼠相比有所降低。单次注射细胞抑制药物三天后，与未处理的大鼠相比，普通和净化动物的木糖吸收减少。在无菌大鼠中，未证实细胞抑制剂对木糖吸收有影响。在普通和净化动物中，细胞抑制剂处理后半乳糖吸收未改变，但在无菌大鼠中增加。
