Yamane T, Asztalos B, Nishida M, Masuzawa T, Takiura K, Taenaka Y, Konishi Y, Miyazoe Y, Ito K
Mechanical Engineering Laboratory, Tsukuba, Japan.
Artif Organs. 1998 May;22(5):375-80. doi: 10.1046/j.1525-1594.1998.06126.x.
With a 250% scaled-up pump model, high speed video camera, and argon ion laser light sheet, flow patterns related to hemolysis were visualized and analyzed with 4 frame particle tracking software. Different flow patterns and shear distributions were clarified by flow visualization for pumps modified to have different hemolysis levels. A combination of in vitro hemolysis tests, flow visualization, and CFD analysis suggested a close relationship between hemolysis and high shear caused by small impeller/casing gaps. Because arbitrary cross sections can be illuminated by laser light sheet, flow visualization is a useful tool in finding locations related to hemolysis in the design process of rotary blood pumps.
使用放大250%的泵模型、高速摄像机和氩离子激光片光源，通过四帧粒子跟踪软件对与溶血相关的流动模式进行可视化和分析。通过对具有不同溶血水平的改良泵进行流动可视化，明确了不同的流动模式和剪切分布。体外溶血试验、流动可视化和计算流体动力学（CFD）分析相结合，表明溶血与小叶轮/泵壳间隙导致的高剪切力之间存在密切关系。由于激光片光源可以照亮任意横截面，流动可视化是在旋转血泵设计过程中寻找与溶血相关位置的有用工具。
