Nakata K, Ohashi Y, Tayama E, Ohtsuka G, Takami Y, Mueller J, Glueck J, Nosé Y
Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA.
Artif Organs. 1998 May;22(5):411-3. doi: 10.1046/j.1525-1594.1998.06127.x.
The rotary blood pump will be an implantable left ventricular assist device (LVAD) in the near future. However, the best control method and the interrelationship between the rotary blood pump and native heart functions are unclear. An estimation was made of the native heart cardiac output from the change of an LVAD's outflow waveform. The mock circulation loop was composed of an aortic compliance chamber, left arterial chamber, total artificial heart as a native heart, and a rotary blood pump that was placed as an LVAD with left ventricular drainage. The fast Fourier transform (FFT) technique was utilized to analyze the LVAD's outflow waveform and calculate the pulse power index (PPI) to examine a relation between the PPI and total artificial heart (TAH) output. The PPI increased with the increase of the TAH output; there was a positive correlation, and there was an inverse correlation between the PPI and the assist ratio. From this viewpoint, an estimation of the pulsatility change of the LVAD's outflow wave may indicate the native cardiac output.
在不久的将来，旋转式血泵将成为一种可植入式左心室辅助装置（LVAD）。然而，最佳控制方法以及旋转式血泵与天然心脏功能之间的相互关系尚不清楚。通过LVAD流出波形的变化对天然心脏的心输出量进行了估算。模拟循环回路由一个主动脉顺应性腔室、左动脉腔室、作为天然心脏的全人工心脏以及作为带有左心室引流的LVAD放置的旋转式血泵组成。利用快速傅里叶变换（FFT）技术分析LVAD的流出波形并计算脉搏功率指数（PPI），以研究PPI与全人工心脏（TAH）输出之间的关系。PPI随TAH输出的增加而增加；存在正相关，且PPI与辅助比率之间存在负相关。从这个角度来看，对LVAD流出波搏动性变化的估算可能表明天然心脏的心输出量。
