Jacoby A F, Fuller A F, Thor A D, Muntz H G
Vincent Memorial Gynecology Service, Massachusetts General Hospital, Boston.
Gynecol Oncol. 1993 Dec;51(3):404-7. doi: 10.1006/gyno.1993.1312.
Primary leiomyosarcoma of the fallopian tube is an extremely uncommon neoplasm. We report a 39-year-old premenopausal woman with leiomyosarcoma confined to the right fallopian tube, who is alive without evidence of disease 2 years after surgical resection followed by adjuvant doxorubicin and cisplatin chemotherapy. An accompanying literature review indicates that the clinical signs and symptoms of fallopian tube sarcomas are usually nonspecific and include lower abdominal pain and pelvic pressure. The age at diagnosis varies from 21 to 70 years, with a median of 47 years. Prognosis is poor, however, several longterm survivors have been reported. The primary treatment remains surgical excision, although adjunctive chemotherapy or radiation may be of some benefit.
原发性输卵管平滑肌肉瘤是一种极为罕见的肿瘤。我们报告了一名39岁的绝经前女性,其平滑肌肉瘤局限于右侧输卵管,在手术切除并接受阿霉素和顺铂辅助化疗后2年,仍然存活且无疾病迹象。附带的文献综述表明,输卵管肉瘤的临床症状和体征通常不具有特异性,包括下腹部疼痛和盆腔压迫感。诊断年龄从21岁至70岁不等,中位数为47岁。预后较差,不过,已有数例长期存活者的报告。尽管辅助化疗或放疗可能有一定益处,但主要治疗方法仍是手术切除。