[Variable changes in immune reactivity and stress-sensitivity as a factor of selection of adaptation strategy under unfavorable conditions].

Experimental data are provided which substantiate the concept on reciprocal changes in immune reactivity and stress sensitivity as a basis for selection of adaptation strategy under unfavorable conditions. The data obtained suggest that transition from the resistant (stress) strategy of adaptation to hypobiosis is a prerequisite for maintenance of the immune reactivity under extreme conditions. Stimulation of the immune system per se may provide for transition from stress to the tolerant (hypobiotic) strategy of adaptation.