Suppr超能文献

工业走廊的癌症发病率:最新情况

Cancer incidence in the industrial corridor: an update.

作者信息

Chen V W, Andrews P A, Wu X C, Correa C N, Fontham E T

机构信息

Department of Pathology, Louisiana State University Medical Center at New Orleans 70112-1393, USA.

出版信息

J La State Med Soc. 1998 Apr;150(4):158-67.

PMID:9610070
Abstract

Because of the high density of industries along the Lower Mississippi River, there is a concern about adverse impact on health, including cancer, among residents in these parishes. This study provides an update of cancer incidence in the Industrial Corridor for the period 1989-93. Age-adjusted cancer incidence rates were calculated for the seven-parish study area from Baton Rouge down to, but not including, New Orleans. Rates were also computed for the entire state of Louisiana and for the combined Surveillance, Epidemiology and End Results (SEER) program. Cancer incidence rates for the Industrial Corridor are either similar to, or lower than, the combined SEER rates for most of the common cancers as well as for rare tumors. The only two exceptions are lung cancer in white males and kidney cancer in white females that are significantly elevated when compared to the SEER averages. Significantly lower rates are found among white males for cancers of kidney, brain, and nervous system, and melanoma; among black males, cancers of all sites combined, oral cavity, stomach, rectum, and prostate, Hodgkin's disease, and non-Hodgkin's lymphoma; among white females, cancers of all sites combined, cervix, uterine corpus, ovary, bladder, and melanoma; and among black females, cancers of all sites combined, oral cavity, lung, breast, ovary, and melanoma. The persistent excess of lung cancer has led to the development of a multi-agency project to evaluate the impact of potential environmental exposures, genetic susceptibility, and their interactions on lung cancer risk. The findings also confirm the urgent need to include and strengthen tobacco prevention and cessation programs in our cancer control activities.

摘要

由于密西西比河下游沿岸工业密集,人们担心这些教区的居民健康会受到不利影响,包括患癌症。本研究提供了1989 - 1993年工业走廊地区癌症发病率的最新情况。计算了从巴吞鲁日到新奥尔良(不包括新奥尔良)的七个教区研究区域的年龄调整癌症发病率。还计算了路易斯安那州全州以及综合监测、流行病学和最终结果(SEER)项目的发病率。工业走廊地区的大多数常见癌症以及罕见肿瘤的癌症发病率与SEER综合发病率相似或更低。仅有的两个例外是白人男性的肺癌和白人女性的肾癌,与SEER平均水平相比显著升高。白人男性中肾癌、脑癌和神经系统癌以及黑色素瘤的发病率显著较低;黑人男性中所有部位综合癌症、口腔癌、胃癌、直肠癌和前列腺癌、霍奇金淋巴瘤和非霍奇金淋巴瘤的发病率显著较低;白人女性中所有部位综合癌症、宫颈癌、子宫体癌、卵巢癌、膀胱癌和黑色素瘤的发病率显著较低;黑人女性中所有部位综合癌症、口腔癌、肺癌、乳腺癌、卵巢癌和黑色素瘤的发病率显著较低。肺癌持续高发促使开展了一个多机构项目,以评估潜在环境暴露、遗传易感性及其相互作用对肺癌风险的影响。研究结果还证实了在我们的癌症控制活动中纳入并加强烟草预防和戒烟项目的迫切需求。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验