Mohr W, Wild A
Z Rheumatol. 1976 Jul-Aug;35(7-8):301-11.
Morphological studies were performed on Wistar-AF/Han-EMD-SPF-rats with adjuvant disease of 3 tp 14 months duration. Synovitis was observed in the noninjected paw up to the 6th month. While in the central bones resorption and new bone formation had ceased about the 7th month, periostal bone resorption proceeded until the 14the month. Morphological end results of the longlasting disease were pannus formation and fibrous ankylosis of the joints and severe sclerosis of the affected bones. Amyloid deposits were never observed.
对患有持续3至14个月佐剂性疾病的Wistar-AF/Han-EMD-SPF大鼠进行了形态学研究。在未注射的爪子中观察到滑膜炎持续至第6个月。虽然在中央骨骼中，吸收和新骨形成在大约第7个月时停止，但骨膜骨吸收一直持续到第14个月。这种长期疾病的形态学最终结果是关节形成血管翳和纤维性强直，以及受影响骨骼的严重硬化。从未观察到淀粉样沉积物。
