Berek K, Margreiter J, Willeit J
Universitätsklinik für Neurologie, Universitätsklinik für Anästhesiologie, Innsbruck, Osterreich.
Wien Klin Wochenschr. 1998 Apr 10;110(7):243-52.
Polyneuropathy developing in critically ill patients ("critical illness polyneuropathy"--CIP) is diagnosed with increasing frequency in intensive care units. CIP is an axonal polyneuropathy leading to difficulties in weaning from artificial ventilation and symmetrical flaccid tetraparesis. Pathogenetically CIP is considered to be part of the multiple organ dysfunction syndrome (MODS) in the course of sepsis or systemic inflammatory response syndrome (SIRS). The incidence of CIP in septic patients with MODS ranges from 50% to 70%. Electroneurography (ENG) and electromyography (EMG) are essential diagnostic procedures. The mortality in patients with CIP is higher than in patients without CIP. Depending on the severity of CIP, recovery of neurological function in survivors is usually relatively good.
重症患者中发生的多神经病（“重症多神经病”——CIP）在重症监护病房中的诊断频率越来越高。CIP是一种轴索性多神经病，可导致脱机困难和对称性弛缓性四肢轻瘫。从发病机制上讲，CIP被认为是脓毒症或全身炎症反应综合征（SIRS）过程中多器官功能障碍综合征（MODS）的一部分。伴有MODS的脓毒症患者中CIP的发生率为50%至70%。神经电图（ENG）和肌电图（EMG）是重要的诊断程序。CIP患者的死亡率高于无CIP的患者。根据CIP的严重程度，幸存者的神经功能恢复通常相对较好。
