Qiu H, Du B, Liu D
Department of Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Wai Ke Za Zhi. 1997 Jul;35(7):402-5.
We defined the epidemiology of systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) in critically ill patients, and evaluated the procession from SIRS to MODS and the therapeutic strategies. 230 patients were studied prospectively until discharge or death. On admission, the morbidity rate of SIRS was 71.3%. The mortality rate of the patients with SIRS was 18.9%. MODS was developed in 65 patients (28.3%), and 33 patients dided (50.8%). In SIRS patients with non-infectious SIRS, sepsis and septic shock, the morbidity rates of MODS were 22.8%, 61.1% and 85.7%, and the mortality rates were 11.4%, 30.6% and 50.0% respectively. The outcome of critically ill patients may be improved if SIRS is early diagnosed and the body inflammatory response is reglulated properly.
我们定义了危重症患者全身炎症反应综合征（SIRS）和多器官功能障碍综合征（MODS）的流行病学情况，并评估了从SIRS到MODS的病程及治疗策略。前瞻性研究了230例患者，直至其出院或死亡。入院时，SIRS的发病率为71.3%。SIRS患者的死亡率为18.9%。65例患者（28.3%）发生了MODS，33例患者死亡（50.8%）。在非感染性SIRS、脓毒症和感染性休克的SIRS患者中，MODS的发病率分别为22.8%、61.1%和85.7%，死亡率分别为11.4%、30.6%和50.0%。如果能早期诊断SIRS并适当调节机体炎症反应，危重症患者的预后可能会得到改善。
