Chang A, Spencer J M, Kirsner R S
Department of Dermatology & Cutaneous Surgery, University of Miami, FL 33136, USA.
Ostomy Wound Manage. 1998 Apr;44(4):26-30.
The treatment of choice for squamous cell carcinoma arising from chronic ulcer at the lower extremity has traditionally been amputation. Recently, Mohs micrographic surgery has been used as a limb-saving option in selected patients. One of these patients, a 69 year-old white male, presented with a two-year history of a progressive non-healing would and osteomyelitis. A four-month history of an enlarging mass within the ulcer suggested squamous cell carcinoma, which was confirmed by biopsies. The patient was treated with Mohs micrographic surgery for local eradication of the tumor, intravenous antibiotics, and skin grafting.
传统上，下肢慢性溃疡引发的鳞状细胞癌的首选治疗方法是截肢。最近，Mohs显微外科手术已被用作特定患者的保肢选择。其中一名患者是一位69岁的白人男性，有两年进行性不愈合伤口和骨髓炎病史。溃疡内肿块增大四个月的病史提示为鳞状细胞癌，活检证实了这一点。该患者接受了Mohs显微外科手术以局部根除肿瘤、静脉注射抗生素和皮肤移植治疗。
