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[遗传性缺陷的产前诊断组织]

[Organization of prenatal diagnosis of genetic defects].

作者信息

Weise W, Bernoth E, Quent P

出版信息

Zentralbl Gynakol. 1976;98(12):705-13.

PMID:961173
Abstract

The prenatal detection of genetic defects can make concrete predictions on definite diseases that are to be expected. In the indication catalogue of the prenatal diagnosis from the amniotic fluid the chromosomal anomalies are predominant. The basis and the potential consequences of the prenatal diagnosis are surgical treatments and highly differentiated methods which may have consequences on the fetus and on the pregnant woman. Therefore the structure of a prenatal diagnostics centre must to a great extent observe the "Nihil nocere". The most important functions in the prenatal diagnostics are incumbent on the surgical gynaecologist. His duties are the indication and the carrying-out of the surgical treatments and measures for the prenatal diagnostics under consideration of the risks existing. The gynaecologist has either further to care for the pregnancy as a risk pregnancy or at corresponding indication to interrupt it even after the 12th week of pregnancy. On these grounds it is recommended to build up a prenatal diagnostic centre in a gynaecological hospital.

摘要

产前对遗传缺陷的检测能够对预期会出现的特定疾病做出具体预测。在羊水产前诊断的指征目录中,染色体异常占主导地位。产前诊断的基础和潜在后果是手术治疗以及可能对胎儿和孕妇产生影响的高度分化的方法。因此,产前诊断中心的架构在很大程度上必须遵循“切勿伤害”原则。产前诊断中最重要的职责由妇科外科医生承担。其职责是在考虑到存在的风险的情况下,为产前诊断指明并实施手术治疗及措施。妇科医生要么将该妊娠作为高危妊娠继续进行护理,要么在相应指征下,甚至在妊娠12周后终止妊娠。基于这些原因,建议在妇科医院设立产前诊断中心。

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