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[长期服用激素避孕药后子宫颈的细胞学和组织学研究结果]

[Results of cytological and histological studies on the uterine cervix after long-term intake of hormonal contraceptive agents].

作者信息

Ebeling K, Ruckhäberle B, Kühndel K, Schulz S, Krönert M

出版信息

Zentralbl Gynakol. 1976;98(7):385-92.

PMID:961193
Abstract

Cytologic examinations with 880 women having constantly used oral contraceptives from one to eight years show no agglomeration of epithelial atypias if the primary status was clearly in the negative. Among 669 histologically sure atypias of cervix uteri the part of women using oral contraceptives for at least one year is significantly lower in carcinoma in situ as well as in early invasive carcinoma. The differences in dysplasia are not significant. The results are also discussed with regard to the efficiency of permanent control examinations before and during the use of oral contraceptions. The demand of a further intensification of cytodiagnostic is derived from these examinations.

摘要

对880名持续使用口服避孕药1至8年的女性进行的细胞学检查表明,如果初始状态明确为阴性,则不存在上皮细胞异型增生的聚集情况。在669例组织学确诊的子宫颈异型增生中,使用口服避孕药至少一年的女性在原位癌以及早期浸润癌中的比例显著较低。发育异常方面的差异不显著。还就口服避孕药使用前和使用期间进行长期对照检查的效果进行了讨论。这些检查得出了进一步强化细胞诊断的要求。

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