Kawamura M, Kusanagi Y, Satou Y, Itou S, Honma M, Shimoide H
Department of Thoracic Surgery, Nakadohri General Hospital, Akita, Japan.
Nihon Kokyuki Gakkai Zasshi. 1998 Jan;36(1):86-9.
A 42-year-old man with pulmonary disease caused by Mcobacterium xenopi is described. He had a history of alcohol use of over 20 years. He was admitted to another hospital for evaluation of an abnormal chest shadow. A chest X-ray showed a cavitary shadow with infiltration in the right upper lung field. Acid-fast organisms were recognized in sputum and M. xenopi was identified by DNA-DNA hybridization. Although he had been treated with isoniazid, rifampicin, and ethanbutol for 5 years, sputum remained positive on culture and chest X-ray findings did not improve. He was later admitted to our hospital for surgery, and right upper lobectomy was performed. He has remained well for 18 months since the operation. In Japan, cases of the pulmonary infection with M. xenopi are rare. Surgical resection is required when chemotherapy is unsuccessful.
本文描述了一名42岁因偶发分枝杆菌引起肺部疾病的男性患者。他有20多年的饮酒史。因胸部阴影异常入另一所医院评估。胸部X光显示右上肺野有空洞阴影伴浸润。痰中发现抗酸菌，通过DNA-DNA杂交鉴定为偶发分枝杆菌。尽管他接受异烟肼、利福平及乙胺丁醇治疗5年，但痰培养仍为阳性，胸部X光检查结果也未改善。他后来入我院接受手术，行右上叶切除术。术后18个月他一直状况良好。在日本，偶发分枝杆菌肺部感染病例罕见。化疗失败时需要进行手术切除。
