[Discriminant studies of immunoglobulins in diseases of the liver and biliary tract].

Discriminant-analytical studies of immunoglobulins G, A and M in 54 persons with a healthy liver and in 476 persons with various diseases of the liver and biliary tracts, and also calculation of correlations between the extent of proliferation of the hepatic mesenchyma and the concentrations of serum immunoglobulin led to the following conclusions: changes in the behaviour of immunoglobulins were specific of the organ and the disease, of limited significance in the diagnosis of diseases of the liver and biliary tracts. Dependence of the quantitative values of immunoglobulins on the activity of hepatic mesenchyma permitted to determine the significance of the indices for the observation over the course of the disease and for its prognosis. However, in the assessment of these changes one should take into consideration the influence produced on the immunoglobulinogram of extrahepatic concomitant disease, and also different individual capacity of the organism to immunoglobulin synthesis.