Nilius R, Busse Kh I, Tsipprikh B, Rat F V
Zh Mikrobiol Epidemiol Immunobiol. 1976(3):120-6.
Discriminant-analytical studies of immunoglobulins G, A and M in 54 persons with a healthy liver and in 476 persons with various diseases of the liver and biliary tracts, and also calculation of correlations between the extent of proliferation of the hepatic mesenchyma and the concentrations of serum immunoglobulin led to the following conclusions: changes in the behaviour of immunoglobulins were specific of the organ and the disease, of limited significance in the diagnosis of diseases of the liver and biliary tracts. Dependence of the quantitative values of immunoglobulins on the activity of hepatic mesenchyma permitted to determine the significance of the indices for the observation over the course of the disease and for its prognosis. However, in the assessment of these changes one should take into consideration the influence produced on the immunoglobulinogram of extrahepatic concomitant disease, and also different individual capacity of the organism to immunoglobulin synthesis.
对54名肝脏健康者以及476名患有各种肝脏和胆道疾病者的免疫球蛋白G、A和M进行判别分析研究，并计算肝间质增生程度与血清免疫球蛋白浓度之间的相关性，得出以下结论：免疫球蛋白行为的变化具有器官和疾病特异性，对肝脏和胆道疾病的诊断意义有限。免疫球蛋白定量值对肝间质活性的依赖性有助于确定这些指标对疾病进程观察及其预后的意义。然而，在评估这些变化时，应考虑肝外伴随疾病对免疫球蛋白谱的影响，以及机体对免疫球蛋白合成的不同个体能力。
