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耳聋与慢性耳蜗内电刺激对中枢听觉通路的影响。

The consequences of deafness and chronic intracochlear electrical stimulation on the central auditory pathways.

作者信息

Hardie N A

机构信息

Department of Otolaryngology, University of Melbourne, Parkville, Victoria, Australia.

出版信息

Clin Exp Pharmacol Physiol. 1998 May;25(5):303-9. doi: 10.1111/j.1440-1681.1998.tb02356.x.

Abstract
  1. Auditory deprivation can result in significant morphological and physiological changes within the central auditory nervous system. These changes are generally more pronounced when the onset of deafness occurs early in development, as is the case with congenitally deaf children. 2. A review of the auditory plasticity literature suggests that some of these deafness-induced changes may be preventable or partially reversible by electrical stimulation of the auditory nerve. 3. With the increasing application of cochlear implants in congenitally deaf children, it is important to evaluate the consequences of introducing electrical stimulation to the developing auditory nervous system.
摘要
  1. 听觉剥夺可导致中枢听觉神经系统内显著的形态和生理变化。当耳聋在发育早期发生时,这些变化通常更为明显,先天性耳聋儿童的情况就是如此。2. 对听觉可塑性文献的综述表明,通过听觉神经的电刺激,这些由耳聋引起的变化中的一些可能是可预防的或部分可逆的。3. 随着人工耳蜗在先天性耳聋儿童中的应用日益增加,评估对发育中的听觉神经系统引入电刺激的后果很重要。

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