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一名失聪患者的耳蜗刺激激活听觉皮层

Activation of the auditory cortex by cochlear stimulation in a deaf patient.

作者信息

Pelizzone M, Hari R, Mäkelä J, Kaukoranta E, Montandon P

出版信息

Neurosci Lett. 1986 Jul 24;68(2):192-6. doi: 10.1016/0304-3940(86)90140-0.

DOI:10.1016/0304-3940(86)90140-0
PMID:3755811
Abstract

We have recorded cerebral electric and magnetic responses to electric stimulation of the auditory nerve in a deaf patient with multichannel cochlear prosthesis. The electric response peaked with a vertex-negative deflection at 65 ms. Clear magnetic responses, coinciding with the vertex potential, were obtained only over the hemisphere ipsilateral to the stimulation; the field pattern indicated activation of the auditory cortex within the Sylvian fissure. The results suggest modification of the central auditory pathways in this patient deaf from early childhood.

摘要

我们记录了一名使用多通道人工耳蜗的失聪患者在听神经电刺激下的脑电和磁反应。电反应在65毫秒时以顶点负向偏转达到峰值。仅在刺激同侧的半球上获得了与顶点电位一致的清晰磁反应;场模式表明颞叶沟内听觉皮层被激活。结果表明该自幼失聪患者的中枢听觉通路发生了改变。

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1
Activation of the auditory cortex by cochlear stimulation in a deaf patient.一名失聪患者的耳蜗刺激激活听觉皮层
Neurosci Lett. 1986 Jul 24;68(2):192-6. doi: 10.1016/0304-3940(86)90140-0.
2
Cortical activity evoked by a multichannel cochlear prosthesis.
Acta Otolaryngol. 1987 May-Jun;103(5-6):632-6.
3
Response of the primary auditory cortex to electrical stimulation of the auditory nerve in the congenitally deaf white cat.先天性耳聋白猫初级听觉皮层对听神经电刺激的反应
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The consequences of deafness and chronic intracochlear electrical stimulation on the central auditory pathways.耳聋与慢性耳蜗内电刺激对中枢听觉通路的影响。
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Passive stimulation and behavioral training differentially transform temporal processing in the inferior colliculus and primary auditory cortex.被动刺激和行为训练以不同方式改变下丘和初级听觉皮层的时间处理。
J Neurophysiol. 2017 Jan 1;117(1):47-64. doi: 10.1152/jn.00392.2016. Epub 2016 Oct 12.
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Functional MR imaging of the auditory cortex with electrical stimulation of the promontory in 35 deaf patients before cochlea implantation.35名聋人患者人工耳蜗植入术前经鼓岬电刺激的听觉皮层功能磁共振成像
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[Experiences with the implantation of a multichannel electrode in the acoustic nerve].
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引用本文的文献

1
Neural prostheses and brain plasticity.神经假体和大脑可塑性。
J Neural Eng. 2009 Dec;6(6):065008. doi: 10.1088/1741-2560/6/6/065008. Epub 2009 Oct 23.
2
Cochlear implants and brain plasticity.人工耳蜗与大脑可塑性。
Hear Res. 2008 Apr;238(1-2):110-7. doi: 10.1016/j.heares.2007.08.004. Epub 2007 Sep 1.
3
Cochlear implants and brain stem implants.人工耳蜗和脑干植入物。
Br Med Bull. 2002;63:183-93. doi: 10.1093/bmb/63.1.183.