[京都啡肽对匹鲁卡品点燃大鼠海人酸诱发癫痫发作活动的影响]
[Effect of kyotorphin on the seizure activity induced by kainic acid during picrotoxin kindling in rats].
作者信息
Brusentsov A I
机构信息
State Medical University, Odessa, Ukraine.
出版信息
Ross Fiziol Zh Im I M Sechenova. 1998 Jan-Feb;84(1-2):115-8.
PMID:9612866
Abstract
In Wistar rats, the ED-50 of kainic acid induced clonic seizures. In early and postponed periods of kindling, the ED-50 decreased by 2,0 to 1.5 times. Kyotorphin did not affect the ED-50 of kainic acid in postponed periods.
摘要
在Wistar大鼠中，海藻酸诱导阵挛性癫痫发作的半数有效剂量（ED-50）。在点燃的早期和延迟期，ED-50降低了2.0至1.5倍。京都啡肽在延迟期不影响海藻酸的ED-50。
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