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[印防己毒素诱导大鼠点燃过程中淋巴细胞增殖转化的变化]

[Changes in the blastogenic lymphocyte transformation during kindling induced by picrotoxin in rats].

作者信息

Brusentsov A I, Moroz V V, Suprun S A, Pomazanova T N, Shandra A A, Godlevskiĭ L S

机构信息

State Medical University, Odessa, Ukraine.

出版信息

Ross Fiziol Zh Im I M Sechenova. 1998 Mar;84(3):233-7.

PMID:9742597
Abstract

Picrotoxin-induced kindling was shown to suppress the blastogenic response to bacterial lipopolysaccharide and phytogemagglutinin in male Wistar rats. The delta-sleep-inducing peptide as well as carbamazepine prevented the epileptogenic effects of picrotoxin. Carbamazepine was also effective against decreasing of phytogemagglutinin-induced blastogenic response.

摘要

在雄性Wistar大鼠中,已表明印防己毒素诱导的点燃可抑制对细菌脂多糖和植物血凝素的增殖反应。δ-睡眠诱导肽以及卡马西平可预防印防己毒素的致癫痫作用。卡马西平对植物血凝素诱导的增殖反应降低也有效。

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