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[胚胎发生早期人类大脑中突触联系的发育]

[Development of synaptic contacts in the human brain during the early stages of embryogenesis].

作者信息

Ivanshina A Z

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(7):983-9.

PMID:961300
Abstract

The author studied the ultrastructure of forming synaptical contacts in the human brain at the early stages of development (7--8 and 9--11 week embryos). It was established that during the 7--8th week of the embryo ontogenesis the brain has already contacts of the puncta adhaerentia type and structures which by several signs can referred to transitory stages in the formation of synapses. During this period of development contacts between the axons of neuroblasts were encountered more frequently that those between the axons and bodies of nervous cells. During the 9--11th weeks of embryogenesis the human brain acquires more contacts between both the axons and the neuroblasts. At this stage there is a first appearance of synaptical structures, similar to functionally and morphologically mature synapses.

摘要

作者研究了人类大脑发育早期阶段(7 - 8周和9 - 11周胚胎)形成突触接触的超微结构。结果表明,在胚胎发育的第7 - 8周,大脑已经有粘着斑类型的接触以及一些根据若干特征可被认为是突触形成过渡阶段的结构。在这个发育阶段,成神经细胞轴突之间的接触比轴突与神经细胞体之间的接触更频繁。在胚胎发育的第9 - 11周,人类大脑中轴突与成神经细胞之间的接触增多。在这个阶段,首次出现了功能和形态上类似于成熟突触的突触结构。

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