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[胚胎发生早期人类大脑中突触联系的发育]

[Development of synaptic contacts in the human brain during the early stages of embryogenesis].

作者信息

Ivanshina A Z

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(7):983-9.

PMID:961300
Abstract

The author studied the ultrastructure of forming synaptical contacts in the human brain at the early stages of development (7--8 and 9--11 week embryos). It was established that during the 7--8th week of the embryo ontogenesis the brain has already contacts of the puncta adhaerentia type and structures which by several signs can referred to transitory stages in the formation of synapses. During this period of development contacts between the axons of neuroblasts were encountered more frequently that those between the axons and bodies of nervous cells. During the 9--11th weeks of embryogenesis the human brain acquires more contacts between both the axons and the neuroblasts. At this stage there is a first appearance of synaptical structures, similar to functionally and morphologically mature synapses.

摘要

作者研究了人类大脑发育早期阶段(7 - 8周和9 - 11周胚胎)形成突触接触的超微结构。结果表明,在胚胎发育的第7 - 8周,大脑已经有粘着斑类型的接触以及一些根据若干特征可被认为是突触形成过渡阶段的结构。在这个发育阶段,成神经细胞轴突之间的接触比轴突与神经细胞体之间的接触更频繁。在胚胎发育的第9 - 11周,人类大脑中轴突与成神经细胞之间的接触增多。在这个阶段,首次出现了功能和形态上类似于成熟突触的突触结构。

相似文献

1
[Development of synaptic contacts in the human brain during the early stages of embryogenesis].[胚胎发生早期人类大脑中突触联系的发育]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(7):983-9.
2
[Possible mechanisms of synapse formation during ontogenesis].[个体发育过程中突触形成的可能机制]
Arkh Anat Gistol Embriol. 1987 May;92(5):20-7.
3
[Development of embryonal brain synapses in the normal state and in maternal alcoholism].[正常状态及母亲酗酒情况下胚胎脑突触的发育]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(2):91-3.
4
Development of synapses between identified sensory neurones and giant interneurones in the cockroach Periplaneta americana.美洲大蠊中已识别的感觉神经元与巨型中间神经元之间突触的发育。
J Embryol Exp Morphol. 1985 Apr;86:227-46.
5
Development of the human cervical spinal cord with reference to synapse formation in the motor nucleus.
J Comp Neurol. 1980 Jun;191(3):495-513. doi: 10.1002/cne.901910311.
6
[The mechanism of the development of the synapse as the basis for its involution].
Biull Eksp Biol Med. 1993 Aug;116(8):214-7.
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Early postnatal development of the monkey neostriatum: a Golgi and ultrastructural study.猕猴新纹状体的生后早期发育:一项高尔基染色和超微结构研究
J Comp Neurol. 1980 Mar 15;190(2):303-31. doi: 10.1002/cne.901900207.
8
[Ultrastructural features of cerebral synapses in schizophrenic patients].[精神分裂症患者大脑突触的超微结构特征]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(7):1065-70.
9
[Structural organization of the synaptic connections of developing neurons in the anterior horns of the spinal cord in early human fetuses].
Biull Eksp Biol Med. 1980 Oct;90(10):494-7.
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[Synapses of the human brain in early prenatal ontogeny].[人类大脑在产前早期个体发育中的突触]
Biull Eksp Biol Med. 1988 Mar;105(3):357-9.

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