Tarasova L A, Kuz'mina L P, Kasparov A A
Med Tr Prom Ekol. 1998(4):1-4.
Human sensitivity to various factors of occupational environment (toxic chemicals, aerosols with mostly fibrogenic effects, etc.) depends on individual hereditary features determining adaptation or dysadaptation with subsequent disease. Studies of propensity and resistance in individuals exposed to occupational hazards should cover analysis of genetic basis for polymorphism in certain biochemical systems determining relationships between hazards detoxication and activation, DNA alteration and repair.
人类对各种职业环境因素(有毒化学物质、主要具有致纤维化作用的气溶胶等)的敏感性取决于决定适应或适应不良及后续疾病的个体遗传特征。对接触职业危害的个体的易感性和抵抗力的研究应包括对某些生化系统中多态性的遗传基础的分析,这些生化系统决定了危害解毒与激活、DNA改变与修复之间的关系。