Mather L E, Tucker G T, Murphy T M, Stanton-Hicks M, Bonica J J
Acta Anaesthesiol Scand. 1976;20(3):207-10. doi: 10.1111/j.1399-6576.1976.tb05030.x.
Hypotension following peridural anesthesia with lidocaine was treated by intravenous injection of ephedrine. The ephedrine relieved the cardiovascular depression, but was associated with a concomitant increase in plasma lidocaine concentrations. This increase may push the plasma lidocaine concentration into the toxic region.
利多卡因硬膜外麻醉后出现的低血压通过静脉注射麻黄碱进行治疗。麻黄碱缓解了心血管抑制，但同时导致血浆利多卡因浓度升高。这种升高可能会使血浆利多卡因浓度进入中毒范围。
