von Essen R, Hölttä A M, Pikkarainen R
Rheumatism Foundation Hospital, Heinola, Finland.
Ann Rheum Dis. 1998 Feb;57(2):107-9. doi: 10.1136/ard.57.2.107.
To establish a quality assessment programme for the diagnosis of crystal arthropathies by synovial fluid (SF) microscopy.
Three or four cytocentrifuge slides prepared from suitable patient SF specimens were distributed to 25-47 predominantly Finnish clinical laboratories once a year. Sodium urate crystals were included in every survey.
Returns for the years 1989-1996 were reviewed. Laboratories that participated in > four surveys made on an average one error a year (range 0.25-2). The error rate for specimens containing abundant crystals was acceptable but it increased considerably for specimens showing few crystals per microscope field. No laboratory characteristic predictive of successful performance was found.
Errors in quality assessment results for crystal identification were much more frequent than in the fields of, for example, clinical chemistry or microbiology. Despite efforts to provide educational feedback, no improvement was seen during the study period. Because of the dearth of data from other parts of the world it is not known for certain whether this study has merely pinpointed a local problem or if the same trend applies elsewhere.
建立一项通过滑液（SF）显微镜检查诊断晶体性关节病的质量评估方案。
每年将从合适患者的SF标本制备的三到四张细胞离心涂片分发给25至47个主要位于芬兰的临床实验室。每次调查均包含尿酸钠晶体。
对1989 - 1996年的反馈结果进行了回顾。参与超过四次调查的实验室平均每年出现一次错误（范围为0.25 - 2）。含有大量晶体的标本的错误率是可接受的，但每个显微镜视野中晶体较少的标本的错误率显著增加。未发现可预测成功表现的实验室特征。
晶体识别质量评估结果中的错误比例如临床化学或微生物学领域更为频繁。尽管努力提供教育反馈，但在研究期间未观察到改善。由于缺乏来自世界其他地区的数据，尚不确定本研究仅仅指出了一个局部问题，还是同样的趋势在其他地方也适用。
