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1983 - 1994年韩国在项目条件下对涂片阳性肺结核患者治疗的队列分析。

Cohort analyses of the treatment of smear-positive pulmonary tuberculosis patients under programme conditions in Korea, 1983-1994.

作者信息

Hong Y P, Kim S J, Lew W J, Lee S H, Lee E K

机构信息

Korean Institute of Tuberculosis/Korean National Tuberculosis Association, Seoul.

出版信息

Int J Tuberc Lung Dis. 1998 May;2(5):365-71.

PMID:9613631
Abstract

SETTING

Cohort analyses of the results of sputum smear-positive pulmonary tuberculosis patients registered in health centres in Korea under programme conditions from 1983 to 1994.

OBJECTIVE

To assess the overall treatment results and their annual changing trend.

DESIGN

Retrospective sample surveys of the nationwide treatment results of registered new smear-positive and retreatment patients.

RESULTS

The numbers of registered smear-positive pulmonary tuberculosis patients have decreased steadily, from over 35000 in 1983 to about 14000 in 1994. Over 90% of health centres, and 60-80% of registered patients, were covered in the cohort analyses. The overall cure rate for all patients was 56% in 1983; this improved to around 80% in the last three years of the period studied, owing to increased use of short-course chemotherapy. Over 5000 patients per year required retreatment during the first four years; this number decreased steadily to less than 700 in 1994, due to the reduction in initial treatment failures.

CONCLUSION

The overall treatment results have improved significantly in Korea, due to the application of short-course chemotherapy.

摘要

背景

对1983年至1994年在韩国各保健中心按项目条件登记的痰涂片阳性肺结核患者的结果进行队列分析。

目的

评估总体治疗结果及其年度变化趋势。

设计

对登记的新涂片阳性和复治患者的全国治疗结果进行回顾性抽样调查。

结果

登记的涂片阳性肺结核患者数量稳步下降,从1983年的超过35000例降至1994年的约14000例。队列分析涵盖了超过90%的保健中心和60 - 80%的登记患者。1983年所有患者的总体治愈率为56%;在所研究时期的最后三年,由于短程化疗的使用增加,治愈率提高到了约80%。在最初四年中,每年有超过5000例患者需要复治;由于初始治疗失败率的降低,这一数字在1994年稳步降至700例以下。

结论

由于短程化疗的应用,韩国的总体治疗结果有了显著改善。

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