Klingler K, Brändli O, Doerfler M, Schluger N, Rom W N
Division of Pulmonary and Critical Care Medicine, NYU Medical Center and Bellevue Chest Service, New York 10016, USA.
Int J Tuberc Lung Dis. 1998 May;2(5):435-7.
Granulomas due to Mycobacterium tuberculosis are rarely observed in valvular structures. When observed, they are associated with disseminated tuberculosis in immunocompromised patients. We report the first case of tuberculous valvular endocarditis isolated in an immunocompetent patient. The patient had severe mitral valve regurgitation due to a perforation of the anterior leaflet of the mitral valve. M. tuberculosis was cultured from the vegetations and no other tuberculous foci were identified. This case exemplifies the protean manifestations of M. tuberculosis infections.
由结核分枝杆菌引起的肉芽肿在瓣膜结构中很少见。当观察到这种情况时，它们与免疫功能低下患者的播散性结核病有关。我们报告了首例在免疫功能正常的患者中分离出的结核性心内膜炎病例。该患者因二尖瓣前叶穿孔而出现严重的二尖瓣反流。从赘生物中培养出结核分枝杆菌，未发现其他结核病灶。该病例体现了结核分枝杆菌感染的多种表现形式。
