Persico A M, Catalano M
Department of NeuroPsychiatric Sciences, S. Raffaele Hospital, Milan, Italy.
Am J Med Genet. 1998 Mar 28;81(2):163-5.
Potential contributions of dopamine transporter (DAT) gene variants to delusional disorder were investigated using association analysis. DAT gene VNTR polymorphisms were assessed in 61 delusional patients and 54 normal controls. No differences were found in either genotypic or allelic distributions. These findings do not support relevant contributions of DAT gene variants to the pathogenesis of delusional disorder.
采用关联分析研究多巴胺转运体(DAT)基因变异对妄想症的潜在影响。对61例妄想症患者和54例正常对照者评估DAT基因VNTR多态性。在基因型或等位基因分布上均未发现差异。这些结果不支持DAT基因变异对妄想症发病机制有相关影响。