Ferguson D J, Hutchison W M, Siim J C
Acta Pathol Microbiol Scand B. 1976 Aug;84(4):189-95. doi: 10.1111/j.1699-0463.1976.tb01924.x.
Toxoplasma gondii undergoing endo-enteric development in the small intestine of the cat affects the ultrastructure of the epithelial cells. The epithelial cells from infected cats have swollen rough endoplasmic reticulum and the mitochondria may be swollen with degenerate cristae. A statistically significant shortening of the microvilli of the epithelial cells was demonstrated. It appeared that the effect on the microvilli length was related to the parasite distribution within the small intestine. These changes occur in both cells with and without parasites present at the level of the sections studied. The abnormalities are quickly rectified after the disappearance of the endo-enteric forms of Toxoplasma.
在猫小肠内进行肠内发育的刚地弓形虫会影响上皮细胞的超微结构。感染猫的上皮细胞糙面内质网肿胀,线粒体可能肿胀且嵴退化。上皮细胞微绒毛在统计学上显著缩短。似乎对微绒毛长度的影响与寄生虫在小肠内的分布有关。在所研究的切片水平上,无论有无寄生虫存在的细胞都会出现这些变化。刚地弓形虫肠内形态消失后,这些异常情况会迅速得到纠正。