Lam D S, Kwok A K, Chew S
Department of Ophthalmology & Visual Sciences, Chinese University of Hong Kong, Prince of Wales Hospital Shatin, N. T., Hong Kong.
Eye (Lond). 1998;12 ( Pt 1):139-40. doi: 10.1038/eye.1998.23.
A diabetic patient who underwent a triple procedure (penetrating keratoplasty, cataract extraction and posterior chamber intraocular lens implantation), developed endophthalmitis caused by Proteus mirabilis. The source of infection was the infected donor cornea, which was imported from Sri Lanka. The organism was resistant to gentamicin, which was the only antibiotic present in the storage medium. On top of an aggressive antibiotic treatment regime (topical, systemic and intravitreal), exchange of the infected with a fresh corneal graft and pars plana vitrectomy were performed. The patient had a speedy recovery and the visual outcome was 20/40 two and a half years after the incident. To our knowledge, post-keratoplasty endophthalmitis caused by P. mirabilis has never been reported in the literature. We report herein such a case with good visual outcome. Newer storage medium, such as Optisol GS, might have a role in preventing keratoplasty-related infection.
一名接受了三联手术(穿透性角膜移植术、白内障摘除术和后房型人工晶状体植入术)的糖尿病患者,发生了由奇异变形杆菌引起的眼内炎。感染源是从斯里兰卡进口的受感染供体角膜。该病菌对庆大霉素耐药,而庆大霉素是储存介质中唯一存在的抗生素。除了积极的抗生素治疗方案(局部、全身和玻璃体腔内)外,还进行了感染角膜与新鲜角膜移植片的置换以及玻璃体切割术。患者恢复迅速,事件发生两年半后视力为20/40。据我们所知,文献中从未报道过由奇异变形杆菌引起的角膜移植术后眼内炎。我们在此报告这样一例视力恢复良好的病例。新型储存介质,如Optisol GS,可能在预防角膜移植相关感染方面发挥作用。