Singh R
Acta Neurochir (Wien). 1976;34(1-4):195-201. doi: 10.1007/BF01405873.
Peroneal nerve allografts four to seven cm in length were transplanted in 36 tissue typed beagle dogs, using a standard microsurgical technique. The influence of tissue typing on nerve regeneration through these grafts was studied with the help of electromyography and histology seven to nine months after nerve implantation. Better regeneration was found through the grafts with compatible than with noncompatible typing. The favourable effect of tissue compatibility became more evident when the length of the graft was longer than four cm. Tissue rejection reaction was much more marked and evident with longer grafts in noncompatible than in compatible groups. Radiation, with tissue typing, did not seem to confer any additional beneficial effect. Compatible tissue typed nerve allografts probably behave more like autografts.
采用标准显微外科技术，将长度为4至7厘米的腓神经同种异体移植物移植到36只经过组织分型的比格犬体内。在神经植入后7至9个月，借助肌电图和组织学研究组织分型对通过这些移植物进行神经再生的影响。结果发现，通过组织分型匹配的移植物比不匹配的移植物再生情况更好。当移植物长度超过4厘米时，组织相容性的有利影响更加明显。在不匹配组中，较长移植物的组织排斥反应比匹配组更明显。放疗结合组织分型似乎并未带来任何额外的有益效果。组织分型匹配的神经同种异体移植物可能表现得更像自体移植物。
