Trojanowski T, Lewelt W, Moszyński K
Acta Neurochir (Wien). 1976;34(1-4):269-72. doi: 10.1007/BF01405883.
Dynamics of the arterial blood pressure changes under the influence of intravenous infusion of sodium nitroprusside (SN) were studied in 12 patients operated on for intracranial aneurysms. Adequate measures were undertaken to avoid blood pressure (BP) changes due to the anaesthetic procedure itself. It was found that the speed of BP lowering corresponded to the rate of infusion, and could easily reach 10 mm Hg/min. After stopping the infusion, the BP recovery rate averaged a mean speed of 8.5 mm Hg/min, varying from 3.8 to 12 mm Hg/min. High speeds of BP lowering and recovery achieved with the use of SN are the main advantages of this hypotensive agent in neurosurgical procedures.
对12例颅内动脉瘤手术患者研究了静脉输注硝普钠（SN）影响下动脉血压变化的动态情况。采取了适当措施以避免麻醉过程本身导致的血压（BP）变化。发现血压降低速度与输注速率相对应，且很容易达到10 mmHg/分钟。停止输注后，血压恢复速率平均为8.5 mmHg/分钟，范围在3.8至12 mmHg/分钟之间。使用SN实现的高速度血压降低和恢复是这种降压药在神经外科手术中的主要优点。
