Van Q N, Shaka A J
Chemistry Department, University of California, Irvine 92697-2025, USA.
J Magn Reson. 1998 May;132(1):154-8. doi: 10.1006/jmre.1998.1404.
In two-dimensional homonuclear experiments, reliable detection of very small cross peaks is sometimes hampered by t1-noise from larger diagonal peaks which have the same F2 frequency. This t1-noise can be selectively removed by recording partial 2D spectra using the double pulsed field gradient spin echo (DPFGSE). Resonances not selected by the DPFGSE do not contribute any t1-noise to the resulting spectrum. The absence of t1-noise from the diagonal peaks render the small cross peaks at the same F2 frequency observable. The success of this technique is shown by partial 2D NOESY and TOCSY spectra.
在二维同核实验中，来自具有相同F2频率的较大对角峰的t1噪声有时会妨碍对非常小的交叉峰的可靠检测。使用双脉冲场梯度自旋回波（DPFGSE）记录部分二维谱可以选择性地去除这种t1噪声。未被DPFGSE选择的共振不会对所得谱图产生任何t1噪声。对角峰不存在t1噪声使得在相同F2频率处的小交叉峰可以被观察到。部分二维NOESY和TOCSY谱图展示了该技术的成功。
