Wang Z, Yang B P, Li H F
Department for Diseases Control of MOH, P. R. China.
Zhonghua Liu Xing Bing Xue Za Zhi. 1995 Apr;16(3):131-6.
In the mid Jun, 1994, a study team organized by MOPH investigated AFP cases in 10 provinces with high prevalence of poliomyelitis (polio). Twenty prefectures and ten counties were selected randomly from each of 10 provinces and relevant prefectures. The team identified 681 AFP cases under 15 years old from 45 hospitals at prefecture level and 13 hospitals at country level based on hospital records from cases occurred during 1991-1994. AFP, Polio, Non-polio AFP and GBS (Guillian-Barre Syndrome) cases aged from 0-14 years scattered around 101 counties (cities) among target population and their average incidences by year were 1.04, 0.48, 0.57 and 0.31 (per 10(5) respectively. Noticingly, the incidence of polio had reduced significantly since 1991, and its proportion among AFP was also reducing from first place yearly since 1991. In addition, over 95% of the polio cases were concentrated in the 4 year olds which indicated that the target population for surveillance and prevention should mainly be focusing on 0-4 year olds. As the incidence of non-polio AFP has been used as a current sensitive index of surveillance system, we noticed that the incidence rates had been significantly different from various regions. According to the analytic data, we recommend that "Rate of non-polio AFP in children 0-14 years of age greater than 1/10(5)" might be a better and more sensitive index for surveillance program in China.
1994年6月中旬，卫生部组织的一个研究小组对10个脊髓灰质炎（脊灰）高流行省份的急性弛缓性麻痹（AFP）病例进行了调查。从10个省份及相关地区中随机选取了20个地区和10个县。该小组根据1991 - 1994年期间病例的医院记录，从45家地级医院和13家县级医院中识别出681例15岁以下的AFP病例。目标人群中0 - 14岁的AFP、脊灰、非脊灰AFP和吉兰 - 巴雷综合征（GBS）病例分布在101个县（市），其年平均发病率分别为1.04、0.48、0.57和0.31（每10万）。值得注意的是，自1991年以来脊灰发病率显著下降，自1991年起其在AFP中的比例也逐年从首位下降。此外，超过95%的脊灰病例集中在4岁儿童，这表明监测和预防的目标人群应主要聚焦于0 - 4岁儿童。由于非脊灰AFP发病率已被用作监测系统的当前敏感指标，我们注意到各地区发病率存在显著差异。根据分析数据，我们建议“0 - 14岁儿童非脊灰AFP发病率大于1/10万”可能是中国监测项目更好、更敏感的指标。
