Chiba Y, Xu A, Li L, Lei T, Takezaki T, Hagiwara A, Yoneyama T, Fujiwara T, Hara M, Yamamoto T
Department of EPI, Shandong Provincial Epidemic Prevention Station, Jinan, China.
Bull World Health Organ. 1994;72(6):915-20.
In Shandong Province, China, programmes were initiated in 1991 for mass immunization against poliomyelitis and for the immediate reporting of acute flaccid paralysis (AFP). The incidence of non-poliomyelitis AFP was found to be 0.46-0.61 cases per 100,000 children per annum. It appeared that illness resembling the Guillain-Barré syndrome was underreported. The incidence of such illness peaked among children aged 2-3 years. Although laboratory investigations have improved, in 1992 they were still inadequate in nearly a third of confirmed poliomyelitis cases. As the prevalence of wild poliovirus declines in China, reliable laboratory support needs to be established and adequately sensitive and specific AFP surveillance be developed if poliomyelitis is to be eradicated.
在中国山东省,1991年启动了针对脊髓灰质炎的大规模免疫规划以及急性弛缓性麻痹(AFP)的即时报告程序。发现非脊髓灰质炎AFP的发病率为每年每10万名儿童0.46 - 0.61例。看来类似吉兰 - 巴雷综合征的疾病报告不足。此类疾病的发病率在2至3岁儿童中达到峰值。尽管实验室检测有所改进,但在1992年,近三分之一的确诊脊髓灰质炎病例的检测仍不充分。随着中国野生脊髓灰质炎病毒流行率的下降,如果要根除脊髓灰质炎,需要建立可靠的实验室支持,并开展足够敏感和特异的AFP监测。