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使用双能X线吸收法(DEXA)对近端股骨干进行假体周围骨密度测量,并与实验性“压配-滑动柄假体”进行比较

[Comparative periprosthetic bone density measurements of the proximal femur shaft using dual energy x-ray absorptiometry (DEXA) with experimental "Press Fit-gliding Stem Prosthesis"].

作者信息

Krüger A, Berli B, Lampert C, Kränzlin C, Morscher E

机构信息

Orthopädische Universitätsklinik Base.

出版信息

Z Orthop Ihre Grenzgeb. 1998 Mar-Apr;136(2):115-25. doi: 10.1055/s-2008-1051293.

DOI:10.1055/s-2008-1051293
PMID:9615973
Abstract

PROBLEM

Periprosthetic bone atrophy caused by stress shielding is one of the problems of non-cemented femoral stems of hip arthroplasty. Stress shielding and thus the loss of bone mass and their dissemination in the proximal part of the femur of conventional non-cemented femoral stems depends on stiffness (E-modules of the material and the geometry) of the implant and on the bonding between implant and bone. All currently implanted non-cemented femoral stems lead to proximal bone loss which goes up to 40-50% of the original bone mineral content. The senior author (E. M.) developed a femoral stem (Press Fit-Gliding Stem PFGS) which shifts relative movements of force-transmission from the bone-implant interface into the interior of the prosthetic system (Inner Bearing-System) and which only transfers forces proximal into the femur.

METHOD

The examinations were made in 21 patients between 1 and 6 years after implantation of a Press Fit-Gliding Stem compared with a normal contralateral femur (12), with bilateral PFGS (3) and other bilateral arthroplasty (6).

RESULTS

In all 21 patients supplied with a PFGS an increase of bone mineral content (BMC) and bone mineral density (BMC) in zone 7 as well as a marked smaller deviation around the mean value in all zones respectively could be noticed.

CONCLUSIONS

With the Dual Energy X-ray Absorptiometry (DEXA)-measurement of bone mineral content (BMC) and bone mineral density (BMD) in all zones according to Gruen could be shown that it is not only possible with regard to a favorable force transmission to avoid the inevitable bone atrophy but on the contrary to induce an increase of bone at the point of local force transmission that is in the region of the calcar femorale (zone 7).

CLINICAL RELEVANCE

The Press Fit-Gliding Stem is still in the clinical test-program.

摘要

问题

应力遮挡导致的假体周围骨萎缩是髋关节置换术非骨水泥型股骨柄的问题之一。传统非骨水泥型股骨柄的应力遮挡以及由此导致的骨量丢失及其在股骨近端的分布取决于植入物的刚度(材料的弹性模量和几何形状)以及植入物与骨之间的结合。目前所有植入的非骨水泥型股骨柄都会导致近端骨丢失,可达原始骨矿物质含量的40% - 50%。资深作者(E.M.)开发了一种股骨柄(压配 - 滑动柄PFGS),它将力传递的相对运动从骨 - 植入物界面转移到假体系统内部(内部轴承系统),并且仅将力近端传递到股骨中。

方法

对21例植入压配 - 滑动柄的患者进行了检查,时间为植入后1至6年,与对侧正常股骨(12例)、双侧PFGS(3例)和其他双侧关节置换术(6例)进行比较。

结果

在所有21例植入PFGS的患者中,均可观察到7区骨矿物质含量(BMC)和骨矿物质密度(BMC)增加,并且所有区域围绕平均值的偏差明显更小。

结论

通过双能X线吸收法(DEXA)根据Gruen测量所有区域的骨矿物质含量(BMC)和骨矿物质密度(BMD),可以表明,不仅在有利的力传递方面有可能避免不可避免的骨萎缩,而且相反,在局部力传递点即股骨距区域(7区)可诱导骨量增加。

临床意义

压配 - 滑动柄仍处于临床试验阶段。

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Z Orthop Ihre Grenzgeb. 1998 Mar-Apr;136(2):115-25. doi: 10.1055/s-2008-1051293.
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