Okuda T, Korogi Y, Ikushima I, Murakami R, Nakashima K, Yasunaga T, Kondo Y, Takahashi M
Department of Radiology, Kumamoto University School of Medicine, Japan.
Br J Radiol. 1998 Mar;71(843):282-90. doi: 10.1259/bjr.71.843.9616237.
The purpose of this study was to evaluate the usefulness of fluid-attenuated inversion recovery (FLAIR) techniques in patients with perinatal hypoxic-ischaemic encephalopathy. 13 patients with a history of perinatal hypoxic-ischaemic encephalopathy (age range 1 month to 3.6 years) underwent T1 and T2 weighted spin echo and FLAIR imaging with a 1.5 T superconducting unit. FLAIR images were qualitatively evaluated in comparison with T1 and T2 weighted images by three experienced radiologists. Quantitative analysis (contrast and contrast-to-noise ratio) was also performed. FLAIR images were preferred to T1 and T2 weighted images in the demonstration of periventricular leukomalacia (PVL), cystic PVL and subcortical lesions near the brain surface. On T1 and T2 weighted images, almost all lesions were demonstrated as hypointense or hyperintense areas, respectively. However, FLAIR images could differentiate cystic lesions by their signal intensities. FLAIR images were not diagnostic in two cases with PVL. In conclusion FLAIR sequences provide useful information in patients with perinatal hypoxic-ischaemic encephalopathy.
本研究的目的是评估液体衰减反转恢复（FLAIR）技术在围产期缺氧缺血性脑病患者中的应用价值。13例有围产期缺氧缺血性脑病病史的患者（年龄范围为1个月至3.6岁）接受了1.5T超导单元的T1加权、T2加权自旋回波和FLAIR成像。由三位经验丰富的放射科医生将FLAIR图像与T1加权和T2加权图像进行定性评估。还进行了定量分析（对比度和对比噪声比）。在显示脑室周围白质软化（PVL）、囊性PVL和脑表面附近的皮质下病变方面，FLAIR图像优于T1加权和T2加权图像。在T1加权和T2加权图像上，几乎所有病变分别表现为低信号或高信号区。然而，FLAIR图像可根据其信号强度区分囊性病变。FLAIR图像对2例PVL患者无诊断价值。总之，FLAIR序列为围产期缺氧缺血性脑病患者提供了有用信息。
