Saraçlar Y, Sekerel B E, Kalayci O, Cetinkaya F, Adalioğlu G, Tuncer A, Tezcan S
Department of Paediatrics, Hacettepe University, School of Medicine, Ankara, Turkey.
Respir Med. 1998 Feb;92(2):203-7. doi: 10.1016/s0954-6111(98)90096-8.
The aim of this study was to determine the prevalence of symptoms suggestive of asthma in children aged 7-14 years in Ankara, Turkey. For this purpose, the recently developed ISAAC (International Study for Asthma and Allergies in Childhood) questionnaire supplemented with six additional questions was issued to parents of 3154 primary school children from 12 schools. A separate page with questions regarding risk factors was also added to the questionnaire. The response rate was 88.3%. The cumulative and 12-month prevalence of wheezing were 14.4 and 4.7% respectively. The prevalence of physician-diagnosed asthma was 8.1%. A family history of atopy was found to be the strongest risk factor for having ever had wheezing (odds ratio (OR) = 2.89, 95% confidence interval (CI) = 2.32-3.60), wheezing in the past 12 months (OR = 3.21, CI = 2.21-4.67), and severe attack (OR = 2.41, CI = 1.36-4.25). Passive smoking was a risk only for having ever had wheezing (OR = 1.33, CI = 1.03-1.76). Increasing age was associated with a lower risk of current wheezing (OR = 0.85, CI = 0.81-0.90) and severe attack (OR = 0.77, CI = 0.67-0.88). Gender, socio-economic level and pet ownership did not appear to be risk factors for asthma-related symptoms. This study, the first epidemiological survey in Ankara, Turkey, using the ISAAC protocol, clearly shows that symptoms suggestive of asthma, albeit lower than in most European countries, are quite common and constitute a major health problem in Turkey.
本研究的目的是确定土耳其安卡拉7至14岁儿童中提示哮喘的症状的患病率。为此,向来自12所学校的3154名小学生的家长发放了最近编制的、补充了六个额外问题的国际儿童哮喘和过敏研究(ISAAC)问卷。问卷中还增加了一页关于危险因素的问题。回复率为88.3%。喘息的累积患病率和12个月患病率分别为14.4%和4.7%。医生诊断为哮喘的患病率为8.1%。发现特应性家族史是曾经喘息(优势比(OR)=2.89,95%置信区间(CI)=2.32 - 3.60)、过去12个月内喘息(OR = 3.21,CI = 2.21 - 4.67)和严重发作(OR = 2.41,CI = 1.36 - 4.25)的最强危险因素。被动吸烟仅是曾经喘息的一个危险因素(OR = 1.33,CI = 1.03 - 1.76)。年龄增加与当前喘息(OR = 0.85,CI = 0.81 - 0.90)和严重发作(OR = 0.77,CI = 0.67 - 0.88)的风险降低相关。性别、社会经济水平和养宠物似乎不是哮喘相关症状的危险因素。这项在土耳其安卡拉首次使用ISAAC方案进行的流行病学调查清楚地表明,提示哮喘的症状尽管低于大多数欧洲国家,但相当常见,并且在土耳其构成一个主要的健康问题。