儿童系统性红斑狼疮的预后

The prognosis of childhood systemic lupus erythematosus.

作者信息

Walravens P A, Chase H P

出版信息

Am J Dis Child. 1976 Sep;130(9):929-33. doi: 10.1001/archpedi.1976.02120100019003.

DOI:10.1001/archpedi.1976.02120100019003

Abstract

A retrospective analysis of 50 patients with childhood systemic lupus erythematosus seen during the past 13 years shows 35 living patients, 13 dead, and 2 lost to follow-up. Fourteen patients were males and 36 females, with the median age of onset 14 years. Clinical presentation was multisystemic in 31, primarily renal in 12, hematologic in 5, and atypical in 2. Renal involvement occurred at some time in all 50 patients. Central nervous system symptoms were present in 22 of 50. Survival in the present series is compared with previously reported survival models in the pediatric age group.

摘要

对过去13年中诊治的50例儿童系统性红斑狼疮患者进行的回顾性分析显示，35例存活，13例死亡，2例失访。14例为男性，36例为女性，发病年龄中位数为14岁。31例临床表现为多系统受累，12例主要为肾脏受累，5例为血液系统受累，2例为非典型表现。所有50例患者均有肾脏受累。50例中有22例出现中枢神经系统症状。将本系列的生存率与先前报道的儿科年龄组生存模型进行比较。