Le Cam Y, Tuel N, Zimbacca F, Bousser J, Guivarch G
Service d'accueil des urgences, Centre hospitalier de Saint-Brieuc.
Rev Pneumol Clin. 1997;53(6):355-9.
The incidence of neoplastic pulmonary embolism is certainly underestimated Necroscopy series report figures varying from 2.9 to 26. The clinical manifestations are similar to those observed in cruoric pulmonary embolism. We report two cases of acute respiratory failure with normal chest X-ray in which the diagnosis was neoplastic pulmonary embolism. The difficulties encountered for diagnosis resulted from the diffuse microvascular nature of the lesions. Perfusion scintigraphy and Swan-Ganz catheterism can be contributive, but certain diagnosis requires pathology examination. Prognosis is very poor. Clinicians should be aware of this pathology and entertain the diagnosis in all cor pulmonale patients with acute respiratory failure and a normal chest X-ray.
肿瘤性肺栓塞的发病率肯定被低估了。尸检系列报告的数据从2.9%到26%不等。其临床表现与血栓性肺栓塞所见相似。我们报告了两例胸部X线正常的急性呼吸衰竭病例,诊断为肿瘤性肺栓塞。诊断遇到困难是由于病变的弥漫性微血管性质。灌注闪烁扫描和Swan-Ganz导管检查可能有帮助,但明确诊断需要病理检查。预后非常差。临床医生应了解这种病理情况,并对所有患有急性呼吸衰竭且胸部X线正常的肺心病患者考虑这一诊断。